Top 5 Disease Clinical Trials
Top 5 Disease Clinical Trials in Latin America – Cohortias de CRO of LATAM
Clinical trials are an essential part of the drug development process, as they allow researchers to test new drugs or treatments for safety and efficacy.
Latin America has become an increasingly important region for clinical trials, as the region offers a diverse population and a wide range of medical conditions.
In this blog post, we will discuss the top 5 disease clinical trials in Latin America.
Cancer Clinical Trials
Cancer is a leading cause of death worldwide, and Latin America is no exception. In recent years, clinical trials have been conducted in the region to test new cancer treatments.
One example is the KEYNOTE-048 trial, which tested the effectiveness of a new immunotherapy treatment called pembrolizumab in patients with head and neck cancer.
The trial was conducted in multiple countries in Latin America, including Brazil, Colombia, and Mexico, and showed promising results in improving survival rates for patients.
Another example of a cancer clinical trial conducted in Latin America is the PRONOUNCE trial, which tested the effectiveness of two different drugs in patients with metastatic prostate cancer.
The trial was conducted in several countries in the region, including Argentina, Brazil, and Mexico, and aimed to improve survival rates and quality of life for patients with this condition.
Cardiovascular Clinical Trials
Cardiovascular diseases, such as heart disease and stroke, are a leading cause of death worldwide. Clinical trials in Latin America have focused on developing new treatments for these conditions.
One example is the LATITUDE trial, which tested the effectiveness of a new drug called sacubitril/valsartan in patients with heart failure.
The trial was conducted in multiple countries in the region, including Brazil, Chile, and Mexico, and showed promising results in improving outcomes for patients with this condition.
Another example of a cardiovascular clinical trial conducted in Latin America is the SOLID-TIMI 52 trial, which tested the effectiveness of a new drug called vorapaxar in patients with a history of heart attack or peripheral artery disease.
The trial was conducted in several countries in the region, including Argentina, Brazil, and Mexico, and aimed to reduce the risk of cardiovascular events in patients with these conditions.
Top 5 Disease Clinical Trials

Infectious Disease Clinical Trials
Infectious diseases, such as HIV/AIDS and tuberculosis, remain a major public health concern in Latin America.
Clinical trials in the region have focused on developing new treatments for these conditions.
One example is the HPTN 071 trial, which tested the effectiveness of a combination of antiretroviral drugs in preventing the transmission of HIV.
The trial was conducted in several countries in the region, including Brazil, Peru, and South Africa, and showed promising results in reducing the risk of HIV transmission.
Another example of an infectious disease clinical trial conducted in Latin America is the REMoxTB trial, which tested the effectiveness of a new drug regimen in treating multidrug-resistant tuberculosis.
The trial was conducted in several countries in the region, including Peru, and showed promising results in improving outcomes for patients with this condition.
Neurological Disease Clinical Trials
Neurological diseases, such as Alzheimer’s disease and multiple sclerosis, are a growing public health concern in Latin America. Clinical trials in the region have focused on developing new treatments for these conditions.
One example is the ARPEGGIO trial, which tested the effectiveness of a new drug called crenezumab in patients with early-stage Alzheimer’s disease.
The trial was conducted in several countries in the region, including Argentina and Brazil, and aimed to slow the progression of the disease in patients.
Another example of a neurological disease clinical trial conducted in Latin America is the RADIANCE trial, which tested the effectiveness of a new drug called ozanimod in patients with relapsing-remitting multiple sclerosis.
The trial was conducted in several countries in the region, including
Respiratory Disease Clinical Trials
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), are a major public health concern in Latin America.
Clinical trials in the region have focused on developing new treatments for these conditions. One example is the LATAM study, which tested the effectiveness of a new drug called benralizumab in patients with severe asthma.
The trial was conducted in several countries in the region, including Brazil and Mexico, and showed promising results in reducing asthma exacerbations in patients.
Another example of a respiratory disease clinical trial conducted in Latin America is the FULFIL trial, which tested the effectiveness of a new drug called triple therapy in patients with COPD.
The trial was conducted in several countries in the region, including Brazil and Mexico, and showed promising results in improving lung function and reducing exacerbations in patients with this condition.
Conclusion
Clinical trials are an important part of the drug development process, as they allow researchers to test new treatments for safety and efficacy.
Latin America has become an increasingly important region for clinical trials, as it offers a diverse population and a wide range of medical conditions.
The top 5 disease clinical trials in Latin America discussed in this blog post include cancer, cardiovascular disease, infectious disease, neurological disease, and respiratory disease.
These trials have shown promising results in improving outcomes for patients with these conditions and offer hope for future treatments in the region.
Top 5 Disease Clinical Trials