Adaptive Clinical Trials in Brazil

Clinical Trials in: Mexico, Argentina, Colombia and Brazil.

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As a leading CRO in LATAM, we specialize in supporting clinical trials throughout the region. Our extensive experience and broad network of clinical sites enable us to execute trials with speed and efficiency, ensuring high patient recruitment and retention rates.

Adaptive Clinical Trials in Brazil

Adaptive Clinical Trials in Brazil – Human Trials LATAM

Clinical trials play a crucial role in advancing medical knowledge and improving patient care. In recent years, adaptive clinical trials have gained recognition as a groundbreaking approach that offers flexibility and efficiency in drug development. Brazil has emerged as a leading destination for adaptive clinical trials, attracting researchers, pharmaceutical companies, and patients from around the globe.

This blog post aims to explore the concept of adaptive clinical trials, highlight Brazil’s growing significance in this field, and discuss the potential benefits and challenges associated with conducting adaptive trials in the Brazilian healthcare landscape.

Understanding Adaptive Clinical Trials

Traditional clinical trials typically adhere to a fixed protocol, where researchers establish predetermined parameters such as sample size and duration before initiating the study. In contrast, adaptive clinical trials allow for modifications to the trial design as data accumulates, enabling researchers to refine their approach based on emerging evidence.

By incorporating adaptations such as sample size reassessment, treatment arm modifications, or even study termination, adaptive trials optimize efficiency, reduce costs, and accelerate the drug development process. Moreover, these trials enhance patient safety by identifying ineffective treatments or harmful side effects earlier.

The Emergence of Adaptive Clinical Trials in Brazil

Brazil has rapidly become a significant hub for cutting-edge clinical research, particularly in the realm of adaptive trials. Several factors contribute to Brazil’s prominence in this field. Firstly, the country boasts a vast and diverse patient population, providing an ideal setting for trials with larger sample sizes and improved representation.

Secondly, Brazil has a well-regulated healthcare system, with agencies like the National Health Surveillance Agency (ANVISA) ensuring patient safety and ethical practices in clinical research. This favorable environment fosters collaboration between international pharmaceutical companies, contract research organizations (CROs), and Brazilian research institutions.

Additionally, Brazil’s robust research infrastructure, highly skilled healthcare professionals, and strategic geographical location make it an attractive destination for sponsors seeking to conduct adaptive trials. The country’s commitment to scientific advancement and innovation further enhances its appeal in the global clinical trial landscape.

Adaptive Clinical Trials in Brazil

Real-World Evidence Studies in Brazil

Adaptive Clinical Trials in Brazil

Benefits of Conducting Adaptive Clinical Trials in Brazil

By embracing adaptive clinical trials, Brazil stands to gain numerous advantages in healthcare research. Firstly, adaptive trial designs can reduce the time required to bring new therapies to market, benefiting patients who urgently need innovative treatments.

Moreover, the real-time adjustments allowed by adaptive trials increase the likelihood of successful outcomes while minimizing exposure to ineffective or potentially harmful interventions. This approach optimizes resource allocation by focusing on the most promising treatment arms, thereby reducing the overall cost of drug development.

Additionally, Brazil’s diverse patient population provides valuable data on the efficacy and safety of drugs across different ethnic groups and medical conditions. This information contributes to the development of personalized and effective healthcare interventions, benefiting patients not only in Brazil but also worldwide.

Challenges and Future Perspectives

While adaptive clinical trials hold great promise, they also present certain challenges.

The dynamic nature of these trials requires a high level of statistical expertise and advanced trial design capabilities. Investing in training programs and fostering collaboration among researchers, regulatory authorities, healthcare professionals, and patient advocacy groups is crucial to ensure the successful implementation of adaptive trials in Brazil.

Furthermore, Brazil needs to strengthen its research infrastructure and improve data-sharing practices to maximize the potential of adaptive clinical trials. Leveraging technological advancements and establishing robust data collection and analysis frameworks can further enhance Brazil’s capabilities in conducting adaptive trials and contribute to the advancement of global healthcare.


Adaptive clinical trials represent a significant advancement in healthcare research, and Brazil’s growing prominence in conducting such trials underscores its commitment to scientific innovation and progress. With its diverse patient population, well-regulated healthcare system, and strong research infrastructure, Brazil is well-positioned to be at the forefront of adaptive clinical trials.

By embracing adaptive trial designs, Brazil can accelerate the development of innovative therapies, improve patient outcomes, and contribute to the global advancement of healthcare. The flexibility and efficiency offered by adaptive trials can lead to faster drug approvals, ensuring that patients have access to life-saving treatments in a timely manner.

Adaptive Clinical Trials in Brazil

Source: Duke Clinical Research Institute

Adaptive Clinical Trials in Brazil

Cohortias the CRO of LATAM

Welcome to Cohortias!

of Latin America

Simplify Your Clinical Trials with Our Expert Infrastructure in Latin America

Say goodbye to the complex, costly, and disorganized process of conducting clinical trials. Our infrastructure in Latin America streamlines the launch of studies and ensures adherence to international standards. Schedule a call with us today to discover the path to simplified clinical research in Latin America.

Adaptive Clinical Trials in Brazil

Explore What We Are Doing Better

We define ourselves as a unique team, capable of blending our academic background with a global business mindset to bring the highest standard of quality and operational excellence into clinical research in Latin America.

Early Phase Trials

- First-in-Human Studies.
- Get to patients faster, no IND necessary.
- Valid data for FDA submission.

Rescue Studies

- Regain lost time and boost patient recruitment.
- We work alongside Global CROs to get studies back on track.
- More than 200 sites available.

Phase II & III Trials

- Full-Service Clinical Outsourcing.
- Proven infrastructure that can handle any trial.
- Local Regulatory Experts
- Wide network of sites and physicians.

Medical Devices

- A fast-track platform that will meet your timeline.
- We take care of everything, from shipping requirements all the way to data collection.
Adaptive Clinical Trials in Brazil

Full Service CRO in LATAM

Outsourcing Clinical Trials to Latin America

Unlock the advantages and opportunities of outsourcing clinical trials to Latin America. Diverse patient population, streamlined regulations, and cost-effectiveness

Lower Operating Costs

From lower labor costs to lower costs for rent, utilities, and equipment, you can save money on your clinical trial budget while still ensuring the quality of your trial

Access to Emerging Markets

Latin America offers access to emerging markets, providing an opportunity for pharmaceutical companies to expand their reach and reach new patient populations.

Adaptive Clinical Trials in Brazil

Cohortias is redefining Clinical Research in Latin America

We are committed to become leaders in providing clinical research services in Latin America. Here at Cohortias, we combine our academic roots, proven experience and a large pool of patients from an extensive network of sites.

Our main purpose is to deliver high quality data.

Adaptive Clinical Trials in Brazil

Clinical Research in Latin America

Cohortias has built an extensive and highly reputable network of clinical sites which can access patients in a timely manner and operate within a standard-of-care comparable to the U.S. healthcare system.


  • Site Management

  • Data Management

  • Site Selection

  • Regulatory Submissions

  • Clinical Monitoring

  • Protocol Development


Beta Trials Platform

  • First-in-human studies

Medical Devices

  • Pilot and Pivotal Device Studies

Phases I – III

  • We partner with our clients to bring their products in a fast and efficient manner to the market with the highest quality standards


  • Diabetes/Metabolic Syndromes
  • Infectious Diseases
  • Cardiovascular
  • Neurology
  • Respiratory
  • Oncology

Adaptive Clinical Trials in Brazil

Clinical Research in Latin America

Academic Leadership and Extensive Clinical Site Network for Efficient Clinical Trials

  • Our peer-to-peer management approach guarantees high patient recruitment and retention in any clinical trial

High Speed Execution

  • We offer the quickest start-up times in each country.
  • Efficient Clinical Site Selection and Contracting.
  • Benefit from our extensive network of clinical sites and streamlined contracting process.

Operational Excellence

  • Proven record of delivering rescue studies, we consistently exceed industry performance standards.
  • Our team provides efficient query resolution to keep your trial on track.

Business Insight and Flexibility

  • We offer innovative pricing models and short lines of communication to ensure maximum flexibility and cost-effectiveness.
  • At Cohortias, we prioritize  short lines of communication to ensure efficient collaboration.
  • Swift adaptation to changes in the trial landscape to keep your study on schedule.

Adaptive Clinical Trials in Brazil

We provide our services with offices in:

Colombia &

Daniela Maresca
Daniela Maresca | Country Lead Argentina
Martín Hernández-Torre | CMO
Maritza Rojas | CRA II
Pedro Alvarez | Business Development Manager
Samantha Rodriguez Cohortias
Samantha Rdz. | Start-Up Manager
Adaptive Clinical Trials in Brazil

The Cohortias Team

Adaptive Clinical Trials in Brazil

As the largest South American Contract research Organization, we know the Advantages and Challenges Of the Region

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Adaptive Clinical Trials in Brazil

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