Adaptive Clinical Research in Brazil

Clinical Trials in: Mexico, Argentina, Colombia and Brazil.

Locally-Based, Full Service CRO

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As a leading CRO in LATAM, we specialize in supporting clinical trials throughout the region. Our extensive experience and broad network of clinical sites enable us to execute trials with speed and efficiency, ensuring high patient recruitment and retention rates.

Adaptive Clinical Research in Brazil

Adaptive Clinical Research in Brazil – CRO Partner in LATAM

The world of clinical research is experiencing a transformative shift with the advent of adaptive clinical trials. These innovative trials are characterized by their flexibility, patient-centric approach, and real-time data analysis, revolutionizing the way new medical treatments are developed and tested.

Brazil, renowned for its diverse culture, natural beauty, and vibrant cities, is emerging as a key player in the realm of adaptive clinical research. In this blog post, we will delve into the significance of adaptive clinical research, its advantages, challenges, and Brazil’s growing role in this exciting frontier of medical innovation.

The Evolution of Clinical Research

Clinical research serves as the bedrock of medical advancement, ensuring that new drugs, therapies, and medical devices are rigorously tested for safety and efficacy before reaching patients. Traditionally, clinical trials adhered to a linear and fixed-protocol approach, with predefined parameters and endpoints. While this method has yielded invaluable insights and many successful treatments, it comes with inherent limitations.

These limitations include protracted trial durations, exorbitant costs, and an inability to adapt to emerging data or changing patient demographics. In response to these challenges, adaptive clinical research has emerged as a game-changing approach that customizes trials to individual patients and permits real-time adjustments.

Understanding Adaptive Clinical Research

Adaptive clinical research is a dynamic, patient-focused approach to clinical trials that emphasizes adaptability and responsiveness. Instead of rigidly adhering to protocols, adaptive trials allow for modifications based on accumulating data. This approach acknowledges the uniqueness of patients and the fact that medical treatments may affect individuals differently.

Key Characteristics of Adaptive Clinical Research:

  1. Real-time Data Analysis: Adaptive trials continually analyze incoming data to identify trends, responses, and adverse events, enabling researchers to make informed adjustments as the trial progresses.
  2. Patient-Centric Design: Adaptive trials consider individual patient responses, facilitating personalized treatment plans and reducing the risk of adverse reactions.
  3. Flexible Protocols: Researchers can modify trial parameters, such as dosages, treatment arms, or sample sizes, based on emerging data, optimizing the likelihood of success.
  4. Efficient Resource Allocation: Adaptive trials allocate resources more efficiently, reducing costs and trial durations while maintaining scientific rigor.
  5. Accelerated Decision-Making: The ability to adapt in real time allows for quicker decisions regarding the efficacy and safety of the tested interventions.

Benefits of Adaptive Clinical Research

  1. Faster Drug Development: Adaptive trials enable quicker decision-making, potentially expediting the drug development process and delivering life-saving treatments to patients sooner.
  2. Cost Savings: By utilizing resources more efficiently, adaptive research reduces the financial burden of clinical trials, making drug development more sustainable.
  3. Enhanced Patient Experience: Personalized treatment plans and flexibility in trial design improve the overall experience for participants, potentially increasing patient retention rates.
  4. Improved Trial Success Rates: Adaptive trials can increase the likelihood of identifying effective treatments by adjusting trial parameters based on emerging data.

Adaptive Clinical Research in Brazil

Adaptive Clinical Research in Brazil

Adaptive Clinical Research in Brazil

Brazil is rapidly establishing itself as a prominent center for adaptive clinical research. Several factors contribute to the country’s appeal as a destination for such trials:

  1. Diverse Patient Population: Brazil boasts an ethnically diverse population with various genetic backgrounds and medical histories, making it an ideal location for trials aiming to account for individual differences.
  2. Robust Research Infrastructure: Brazil possesses a well-developed network of research centers, hospitals, and clinical trial facilities, providing the necessary infrastructure and expertise for conducting adaptive trials.
  3. Regulatory Framework: Brazil has established a robust regulatory framework for clinical research, ensuring patient safety and data integrity.
  4. Cost Efficiency: Brazil offers cost advantages compared to some other countries, making it an attractive option for sponsors looking to optimize trial budgets.

Challenges and Considerations

While adaptive clinical research offers numerous advantages, it also presents unique challenges:

  1. Statistical Complexity: Adaptive trials require advanced statistical methods and expertise to ensure the validity of findings.
  2. Regulatory Compliance: Adherence to evolving regulatory guidelines and ethical standards is crucial to maintaining the integrity of adaptive trials.
  3. Data Management: Managing real-time data and making timely decisions can strain data management systems and necessitate robust IT infrastructure.
  4. Patient Consent: Informed consent processes must be adapted to accommodate the dynamic nature of adaptive trials.


Adaptive clinical research is reshaping the landscape of medical research, promising faster, more efficient drug development and improved patient outcomes. Brazil’s burgeoning role in this field underscores the country’s potential to contribute significantly to global healthcare advancements.

As adaptive clinical research continues to gain traction, we can anticipate more innovative therapies and treatments emerging from Brazil, benefiting not only its own population but also patients worldwide.

This evolution represents a significant step forward in the quest to enhance healthcare for all. Brazil’s vibrant culture, natural beauty, and research capabilities are now helping shape the future of medicine.

Adaptive Clinical Research in Brazil

Source: Duke Clinical Research Institute

Welcome to Cohortias!

of Latin America

Simplify Your Clinical Trials with Our Expert Infrastructure in Latin America

Say goodbye to the complex, costly, and disorganized process of conducting clinical trials. Our infrastructure in Latin America streamlines the launch of studies and ensures adherence to international standards. Schedule a call with us today to discover the path to simplified clinical research in Latin America.

Adaptive Clinical Research in Brazil

Explore What We Are Doing Better

We define ourselves as a unique team, capable of blending our academic background with a global business mindset to bring the highest standard of quality and operational excellence into clinical research in Latin America.

Early Phase Trials

- First-in-Human Studies.
- Get to patients faster, no IND necessary.
- Valid data for FDA submission.

Rescue Studies

- Regain lost time and boost patient recruitment.
- We work alongside Global CROs to get studies back on track.
- More than 200 sites available.

Phase II & III Trials

- Full-Service Clinical Outsourcing.
- Proven infrastructure that can handle any trial.
- Local Regulatory Experts
- Wide network of sites and physicians.

Medical Devices

- A fast-track platform that will meet your timeline.
- We take care of everything, from shipping requirements all the way to data collection.
Adaptive Clinical Research in Brazil

Full Service CRO in LATAM

Outsourcing Clinical Trials to Latin America

Unlock the advantages and opportunities of outsourcing clinical trials to Latin America. Diverse patient population, streamlined regulations, and cost-effectiveness

Lower Operating Costs

From lower labor costs to lower costs for rent, utilities, and equipment, you can save money on your clinical trial budget while still ensuring the quality of your trial

Access to Emerging Markets

Latin America offers access to emerging markets, providing an opportunity for pharmaceutical companies to expand their reach and reach new patient populations.

Adaptive Clinical Research in Brazil

Cohortias is redefining Clinical Research in Latin America

We are committed to become leaders in providing clinical research services in Latin America. Here at Cohortias, we combine our academic roots, proven experience and a large pool of patients from an extensive network of sites.

Our main purpose is to deliver high quality data.

Adaptive Clinical Research in Brazil

Clinical Research in Latin America

Cohortias has built an extensive and highly reputable network of clinical sites which can access patients in a timely manner and operate within a standard-of-care comparable to the U.S. healthcare system.


  • Site Management

  • Data Management

  • Site Selection

  • Regulatory Submissions

  • Clinical Monitoring

  • Protocol Development


Beta Trials Platform

  • First-in-human studies

Medical Devices

  • Pilot and Pivotal Device Studies

Phases I – III

  • We partner with our clients to bring their products in a fast and efficient manner to the market with the highest quality standards


  • Diabetes/Metabolic Syndromes
  • Infectious Diseases
  • Cardiovascular
  • Neurology
  • Respiratory
  • Oncology

Adaptive Clinical Research in Brazil

Clinical Research in Latin America

Academic Leadership and Extensive Clinical Site Network for Efficient Clinical Trials

  • Our peer-to-peer management approach guarantees high patient recruitment and retention in any clinical trial

High Speed Execution

  • We offer the quickest start-up times in each country.
  • Efficient Clinical Site Selection and Contracting.
  • Benefit from our extensive network of clinical sites and streamlined contracting process.

Operational Excellence

  • Proven record of delivering rescue studies, we consistently exceed industry performance standards.
  • Our team provides efficient query resolution to keep your trial on track.

Business Insight and Flexibility

  • We offer innovative pricing models and short lines of communication to ensure maximum flexibility and cost-effectiveness.
  • At Cohortias, we prioritize  short lines of communication to ensure efficient collaboration.
  • Swift adaptation to changes in the trial landscape to keep your study on schedule.

Adaptive Clinical Research in Brazil

We provide our services with offices in:

Colombia &

Daniela Maresca
Daniela Maresca | Country Lead Argentina
Martín Hernández-Torre | CMO
Maritza Rojas | CRA II
Pedro Alvarez | Business Development Manager
Samantha Rodriguez Cohortias
Samantha Rdz. | Start-Up Manager
Adaptive Clinical Research in Brazil

The Cohortias Team

Adaptive Clinical Research in Brazil

As the largest South American Contract research Organization, we know the Advantages and Challenges Of the Region

Let Us Guide You Through The Latin American Clinical Research Landscape

Adaptive Clinical Research in Brazil

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